Optimal antithrombotic therapy and vascular access site in the management of acute coronary syndromes
نویسندگان
چکیده
منابع مشابه
[Present and future of antithrombotic therapy in acute coronary syndromes].
Antithrombotic therapy in the management of an acute coronary syndrome is designed to inhibit both the coagulation cascade and platelet activation, thus preventing the development of the pathophysiological consequences of these processes. The main therapeutic approaches used for this purpose are unfractionated heparin, low-molecular-weight heparins, or direct antithrombins, all of them being mo...
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BACKGROUND The Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial demonstrated that bivalirudin monotherapy significantly reduces major bleeding compared with heparin (unfractionated or enoxaparin) or bivalirudin plus a glycoprotein IIb/IIIa inhibitor in acute coronary syndromes. Whether vascular closure devices (VCD) impact these results is unknown. Therefore, this st...
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Patients with diabetes mellitus (DM) and acute coronary syndromes (ACSs) are at particularly high risk for recurrent cardiovascular events, including death. The reason for this increased risk is multifactorial, including underutilization of evidencebased medications in these patients (1). More research is needed to identify both the optimal antithrombotic strategy and duration of therapy, and g...
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The wide variety of anticoagulant and antiplatelet agents available for clinical use has made choosing the optimal antithrombotic regimen for patients with acute coronary syndromes undergoing percutaneous coronary intervention a complex task. While there is no single best regimen, from a risk-benefit ratio standpoint, particular regimens may be considered optimal for different patients. We revi...
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Heartcenter Onze Lieve Vrouwe Gasthuis (OLVG), Amsterdam, The Netherlands; University of Copenhagen, Copenhagen, Denmark; Mount Sinai Medical Center, New York, NY, USA; Department of Medicine, Oslo University Hospital and Oslo University, 0514 Oslo, Norway; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK; Henry Ford Hospital, Detroit, MI, USA; Thorax...
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ژورنال
عنوان ژورنال: European Heart Journal: Acute Cardiovascular Care
سال: 2019
ISSN: 2048-8726,2048-8734
DOI: 10.1177/2048872619875690